The two cannabinoid compounds in the cannabis plant that are found in the highest concentration are CBD and THC. Numerous studies have shown that both these cannabinoids can interact with the endocannabinoid system (ECS). However, its effects on the body are different and due to that, the laws surrounding CBD and THC are completely different in the United States.
If you are looking for a CBD product in the market, you may find that some products contain less than 0.3 % THC. This raises several questions about the differences between these compounds. To know more about how CBD is different from THC, keep on reading this article.
How Do CBD And THC Interact With The Endocannabinoid System?
THC binds to both CB1 and CB2 receptors directly, however, the CB1 receptors have a higher affinity. CBD does not have a strong affinity for either of the two cannabinoid receptors; instead, it acts as an indirect antagonist of cannabinoid agonists, reducing the CB1 and CB2 activating qualities of cannabinoids such as THC. It also interacts with non-cannabinoid receptors such as the TRPV-1 vanilloid receptor and the 5-HT1A receptor.
Which Cannabinoid Has Psychoactive Properties?
Despite their molecular structures being similar, THC and CBD do not have the same psychotropic effects. CBD is not psychoactive, which means it will not give you the “high” that THC does. CBD has a weak affinity for CB1 receptors. In fact, it may prevent THC from attaching to receptors, reducing the euphoric effects.
What Are The Health Benefits Of CBD And THC?
THC and CBD are both used to treat several medical conditions. However, the applications of each chemical differ slightly. CBD is mainly used in the treatment of seizures, inflammatory disorders, anxiety disorders, migraines, etc. On the other hand, THC helps in managing low appetite, muscle spasms, insomnia, glaucoma, etc.
Legality Of CBD And THC
The main difference between these two cannabinoids is their legal status in the United States. Cannabis laws in the United States are constantly changing. Because cannabis and THC are classified as “controlled substances,” they are illegal under federal law.
However, marijuana-related laws have been established in Washington, D.C., and numerous states, making medical cannabis with high THC levels lawful. However, cannabis may require a prescription from a licensed physician. A few states have also legalized cannabis and THC for recreational usage. You should have no trouble purchasing CBD in states where cannabis is allowed for medical or recreational use.